Book Hotels in Lake City, SC
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Top Lake City hotels
The Inn at the Crossroads
"Hotel was very clean and spacious."
Reviewed on May 20, 2026
Staybridge Suites Florence - Civic Center by IHG
"Staff was great good sense of humor late at night. But not my favorite place to stay."
Reviewed on May 26, 2026
Comfort Inn & Suites Florence Center Area
"The staff were very helpful and professional. Check in process was simple and the property was very clean. Plenty of parking too."
Reviewed on May 31, 2026
Quality Inn & Suites Florence Civic Center
"We had a handicapped accessible room, which - surprisingly - is probably the furthest room from the lobby, where breakfast is served."
Reviewed on Jun 1, 2026
Aloft by Marriott Florence
"Never before in my life have I had such a horrible experience at a hotel. Poop in the bed. Just disgusting"
Reviewed on May 30, 2026
Quality Inn & Suites Lake City
"The room has sand on the floor and no toilet paper. We had to go purchase toilet paper"
Reviewed on May 24, 2026
Days Inn by Wyndham Florence Near Civic Center
"The hotel was a great location with the mall and restaurants in walking distance. The staff was nice, check in and out was simple, and it was fairly quiet. The breakfast was not much. Only Belgian waffles, dry cereal with milk, yogurt, and coffee. It would have been nice to have eggs and/or sausages, ..."
Reviewed on Jun 1, 2026
Days Inn by Wyndham Lake City
"The room was great. Very clean. The staff needs lessons in etiquette."
Reviewed on May 17, 2026
3-bedroom house in welcoming Lake City with cool AC
Cheap Lake City hotels
The Inn at the Crossroads
Lake City Hotel & Travel Guide
Within a 6-mile (10-kilometer) radius of the heart of Lake City, with Travelocity's reservations page you can find a limited, yet excellent selection of places to kick your feet up. Within an easy commute to Lake City, travelers will find 2 suitable lodging options.
If you are hoping to find a hotel that is no more than an easy walk from central Lake City, Days Inn Lake City and The Inn at the Crossroads will be perfect.
If you are in the downtown area of Lake City, it is around 13 miles (21 kilometers) to the Signature Boutique Hotel.
Would you like to go further afield? South Carolina Midlands boasts many impressive options. South Carolina Midlands is famous for rolling hills. Commonly visited visitor sights include historic mansions and gardens. In this fascinating part of United States of America adventurous visitors can partake in hiking.
35 miles (59 kilometers) to the northwest of Lake City, you can reach Bishopville, which is where you can enjoy South Carolina Cotton Museum and Lee State Park. A few Bishopville places to stay include the Americas Best Value Inn and Econo Lodge Bishopville. 40 miles (63 kilometers) northwest of Lake City, is Hartsville, which boasts the Fairfield Inn by Marriott Hartsville and Quality Inn. During your time in Hartsville, make your way to the Coker College and Hartsville Museum.
If you are into sports and like to watch thrilling games you and your family could take a trip to Myrtle Beach Speedway, which is found 45 miles (75 kilometers) to the east of Lake City. Find a Travelocity-listed hotel right in the thick of the action at the Bluegreen Vacations Harbour Lights, Ascend Resort Collection or the Hampton Inn Myrtle Beach West.
Florence Regional Airport is a primary arrival point for air travel, and is 25 miles (37 kilometers) from Lake City's downtown. Travelocity-listed accommodation nearby include Hotel Florence, an Ascend Hotel Collection Member and Motel 6 Florence Historic Downtown.
Frequently asked questions
Recent Lake City hotel reviews by fellow wanderers
Days Inn by Wyndham Florence Near Civic Center
"The hotel was a great location with the mall and restaurants in walking distance. The staff was nice, check in and out was simple, and it was fairly quiet. The breakfast was not much. Only Belgian waffles, dry cereal with milk, yogurt, and coffee. It would have been nice to have eggs and/or sausages, but for the price it was not bad."
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